首页|血清3项炎症指标对肛周脓肿部位及严重程度的诊断效能

血清3项炎症指标对肛周脓肿部位及严重程度的诊断效能

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目的:探讨超敏C反应蛋白(hs-CRP)、白细胞(WBC)、中性粒细胞与淋巴细胞比值(NLR)对肛周脓肿的诊断效能.方法:纳入146例肛周脓肿患者作为病例组;同期130例健康体检者作为对照组.检测2组受试者血清炎症指标变化.应用受试者工作特征(ROC)曲线评估hs-CRP、WBC、NLR对肛周脓肿部位及严重程度的诊断效能.结果:高位肛周脓肿的发生与hs-CRP、WBC、中性粒细胞百分数(NEUT%)、CRP、NLR均成正相关(P<0.05),与对照组、低位脓肿组患者比较,上述指标的差异均有统计学意义(P<0.05).hs-CRP、CRP、WBC、NLR、CRP+WBC+NLR、hs-CRP+WBC+NLR诊断高位脓肿与低位脓肿的曲线下面积(AUC值)分别为0.680、0.679、0.619、0.648、0.673、0.679.结论:hs-CRP对肛周脓肿诊断及其严重程度评估均具有较高的预测价值,可在肛周脓肿早期阶段快速诊断,值得临床推广.
Diagnostic value of high-sensitivity C-reactive protein,white blood cell count,neutrophil-to-lympho-cyte ratio in the detection of perianal abscess
Objective:To investigate the expression and diagnostic predictive value of high-sensitivity C-reac-tive protein(hs-CRP),white blood cell(WBC)count,and neutrophil-to-lymphocyte ratio(NLR)in perianal ab-scess.Methods:A total of 146 patients with perianal abscess were included as the case group,while 130 healthy individuals undergoing physical examination during the same period were selected as the control group.The changes in blood routine indicators of the two groups of subjects were examined.Receiver operating characteristic(ROC)curve was used to evaluate the efficacy of hs-CRP,WBC,and NLR in predicting the se-verity of perianal abscess.Results:The occurrence of high perianal abscess is positively correlated with hs-CRP,WBC,NEUT,CRP and NLR(P<0.05);the levels of these indicators are higher than those in the control group and patients with low perianal abscess,and the differences are statistically significant(P<0.05).The area under the curve(AUC)values for the diagnosis of high and low perianal abscesses using hs-CRP,CRP,WBC,NLR,CRP+WBC+NLR,and hs-CRP+WBC+NLR are 0.680,0.679,0.619,0.648,0.673,and 0.679 respectively(P<0.05).Conclusion:The level of hs-CRP has the higher predictive value for the diagnosis and severity assess-ment of perianal abscesses.The use of this indicator can facilitate a simple and rapid diagnosis in the early stage of perianal abscesses and is worthy of clinical promotion.

perianal abscesshigh-sensitivity C-reactive proteinwhite blood cellsneutrophil-to-lymphocyte ratiodiagnostic value

马凰富、王月、张学成、杨涵雯、王晏美、李佳楠

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中日友好医院 肛肠科一部,北京 100029

肛周脓肿 超敏C反应蛋白 白细胞 中性粒细胞与淋巴细胞比值 诊断价值

中日友好医院院级课题中日友好医院自发性研究

2023-NHLHCRF-YYPPLC-ZR-032024-ZF-12

2024

中日友好医院学报
中日友好医院

中日友好医院学报

CSTPCD
影响因子:0.92
ISSN:1001-0025
年,卷(期):2024.38(4)