低镁血症对成人脓毒症患者预后的影响
Effect of hypomagnesemia on the prognosis of adult patients with sepsis/
史艳 1孙彩虹 1王燕 1金瑶瑛 2李涛3
作者信息
- 1. 日照市人民医院重症医学科一病区,山东日照 276826
- 2. 北京中医药大学研究生院,北京 100029
- 3. 中日友好医院重症医学科,北京 100029
- 折叠
摘要
目的:评估低镁血症是否与脓毒症患者的全因院内病死率相关.方法:回顾分析2020年6月-2023年6月中日友好医院重症医学科收治的成人脓毒症患者.将符合纳入标准的患者,根据入科时的血镁水平,分为低镁血症组和正常血镁组.对比分析2组病死率的差异,并应用Logistic回归统计分析病死率的危险因素.结果:285例患者纳入研究,其中低镁血症组114例,病死率29.8％,显著高于正常血镁组(8.2％),差异有统计学意义(P＜0.05).高序贯器官衰竭评分、机械通气、低镁血症是脓毒症患者院内全因病死率的独立危险因素(OR=2.85、3.42、2.32,均P＜0.05).结论:低镁血症是成人脓毒血症患者高院内全因病死率的独立危险因素.
Abstract
Objective:To evaluate whether hypomagnesemia is associated with all-cause in-hospital mortality in adult patients with sepsis.Methods:Adult patients with sepsis admitted to the Intensive Care Unit of Chi-na-Japan Friendship Hospital from June 2020 to June 2023 were retrospectively summarized.Patients meeting the inclusion criteria were divided into the hypomagnesemia group and the normal serum magnesium group ac-cording to the serum magnesium level at admission.The differences in mortality between the two groups were compared and analyzed,and logistic regression was used to analyze the risk factors for mortality.Results:A to-tal of 285 patients were included in the study,among whom 114 patients were in the hypomagnesemia group,with a mortality rate of 29.8％,which was significantly higher than that in the normal serum magnesium group(8.2％)(P＜0.05).High sequential organ failure score,mechanical ventilation,and hypomagnesemia were inde-pendent risk factors for in-hospital all-cause mortality in patients with sepsis(OR=2.85,3.42,2.32,all P＜0.05).Conclusion:Hypomagnesemia is an independent risk factor for high in-hospital all-cause mortality in adult patients with sepsis.
关键词
低镁血症/脓毒症/院内全因病死率Key words
hypomagnesemia/sepsis/all-cause in-hospital mortality引用本文复制引用
基金项目
国家高水平医院临床研究项目(2022-NHLHCRF-LX-02-0124)
出版年
2024
NETL
NSTL
万方数据