Residual digestion and dietary intake risk assessment of thiamethoxam and its metabolite clothianidin in Lycium barbarum
In order to analyze the pesticide residues of thiamethoxam 50％WG in Lycium barbarum,the dietary intake risk of the residues was evaluated.A HPLC/MS tandem mass spectrometry method was established for the determination of thiamethoxam and its metabolite clothianidin in L.barbarum to analyze the final residues of pesticides in L.barbarum and estimate the risk of chronic ingestion of pesticides.The results showed that in the range of 0.01-1.0 mg/L,the linear relationship between the two pesticides was good,and the correlation coefficient was greater than 0.999.The average recoveries were 80.7％-106.6％and the relative standard deviations were 1.4％-4.6％at three supplemental levels(0.01,0.1 and 1.0 mg/kg).Storage stability test showed that both thiamethoxam and clothianidin were stable in L.barbarum after storage for 11 months.The chronic exposure risk of Chinese residents ingestion of thiamethoxam and clothianidin was 16.6％and 3.8％,respectively,much lower than 100％,indicating a low risk of chronic dietary exposure.
万方数据
维普
