qbjective: To improve Central sterile supply department(CSSD) management in order to engage everyone in the management and control of CSSD. METHODS: The reward and penalty provisions of quality management control were laid out, the reward and penalty standards in details were made, which could ensure that each standard was practical. Commend and reward were made in general assembly in order to affirm the performance of rewarded people in CSSD quality management control. RESULTS: The initiative and activeness of quality management control of each section were significantly improved. CONCLUSION: The application of incentive mechanism can motivate the medical staff to attach importance to CSSD management and pay attention to the control of quality management in their surroundings.