首页|非酒精性脂肪肝与胰岛素抵抗相关因素的分析

非酒精性脂肪肝与胰岛素抵抗相关因素的分析

An analysis on the related factors of NAFLD and insulin resistance

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目的:探讨非酒精性脂肪肝与胰岛素抵抗之间的相关关系。方法根据肝脏超声检查结果将纳入病例分为轻、中、重度三组,每组分别测身高、体重、血糖、甘油三酯、胆固醇、胰岛素、丙氨酸氨基转移酶等指标,计算出体重指数(BMI)、胰岛素抵抗指数(HOMA-IR)和β细胞功能指数(HBCI)。比较各组间数据。结果非酒精性脂肪肝患者ALT、血脂、BMI、WHR 均高于对照组(P<0.05)。不同程度的脂肪肝患者之间,其HOMA-IR、HBCI有显著性差异(P<0.05)。脂肪肝组患者HOMA-IR、HBCI的阳性率高于非脂肪肝组(P<0.05)。结论非酒精性脂肪肝患者胰岛素抵抗增加,且随着脂肪肝程度加重,胰岛素抵抗亦加重。
Objective To investigate the relationship between NAFLD and insulin resistance. Methods The Non-alcoholic fatty liver disease patients are divided into mild group, moderate group and severe group by the results of liver color Doppler ultrasonography. Each group were measured height, weight, blood glucose, triglycerides, cholesterol, insulin and ALT to calculate the BMI, HOMA-IR and HBCI for comparison. Results 1.Compared with control group, ALT、triglycerides, cholesterol、BMI、WHR in NAFLD groups were significantly higher (p<0.05). HOMA-IR and HBCI have significant difference in mild group, moderate group and severe group(p<0.05). Patients with NAFLD have more positive tests for HOMA-IR and HBCI than others.Conclusions Patients with NAFLD have more severe insulin resistance.And insulin resistance getting worse is associated with more severe NAFLD.

NAFLDinsulin resistance

王英、柯翌子、赖桂兰

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成都铁路分局医院 610081

非酒精性脂肪肝 胰岛素抵抗

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(1)
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