objective To evaluate the effects of aripiprazole on prolatin, glucose and lipid metabolism of patients with schizophrenia. Method 64 patients with first-episode schizophrenia were treated with aripiprazole. The glucose, prolactin and lipid level were measured before ,4 and 8 weeks after drug administration. Results ①On the 4thweekend, 8thweekend, the levels of serum prolactin in study group had significant differences with that in baseline(P<0.05);②On the 4thweekend, 8thweekend, the levels of Glu,TG,TC in study group had no significant differences with that in baseline(P>0.05). Conclusion Aripiprazole is effective to decrease the level of prolactin and has no effects on glucose and lipid metabolism.
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