A Study on D-Dimer Detection in Differentiation of Acute Pulmonary Embolism and Acute Myocardial Infarction
Objective: To discuss the clinical significance of quantitative detection of D-dimer in the differentiation of acute pulmonary embolism and acute myocardial infarction. Methods: 46 patients with the acute pulmonary embolism, 48 patients with the acute myocardial infarction and 45 healthy subjects were randomly chosen in this research, who received the quantitative detection of plasma D-dimer by Nephstar specific protein analyzer. Results were analyzed by t test. Results: The level of D-dimer in the serum of patients with the pulmonary embolism was significantly higher than the one in the serum of patients with the acute myocardial infarction (P<0.001), but there was no significant difference between the control group and other two groups (P<0.001). Conclusion: The level of D-dimer in the serum of patients with the acute pulmonary embolism is significantly higher than the one in the serum of patients with the acute myocardial infarction, which can be used to differentiate patients with the acute pulmonary embolism and acute myocardial infarction who have the atypical clinical signs. Thus the fast and non-invasive quantitative detection of D-dimer is suitable for the emergency detection and it is worthy to be popularized.
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