Objective:To explore the risk factors of nosocomial infection happened to elderly hospitalized patients in respiratory medicine and develop targeted preventive measures,so as to reduce the incidence of nosocomial infection.Methods:Clinical data of respective 30 elderly hospitalized patients with and without hospital infections in our respiratory medicine at the same period were col ected,compared and analyzed.Results:The risk factors of nosocomial infection are age,comorbidities,with or without invasive procedure,proper use of antimicrobial drugs and hospitalization time(P<0.05).Conclusion:On the basis of taking appropriate preventive measures against the risk factors,it can effectively reduce the incidence of nosocomial infections to strengthen the management and control of hospital infection.