Objective To evaluate the efficacy of cefoperazone - Shubatan in the treatment of acute exacerbations of chronic obstructive pulmonary disease. Methods a retrospective analysis of 100 cases of patients were randomly divided into the observation group of antibiotics with cefoperazone - Shubatan and the control group with ceftazidime antibiotics in our hospital from 2011 January to 2013 January in our hospital, acute exacerbation of chronic obstructive pulmonary disease, al patients were treated for 2 weeks. Results compared the clinical efficacy of the two groups, the observation group the total effective rate was 92%, significantly higher than that in the control group the total efficiency of 78%, there are significant differences P<0.05. The main adverse reactions of the two groups patients were nausea and vomiting, loss of appetite, skin rash, comparison of major adverse reactions of the two groups, the difference had no statistical significance (P>0.05). Conclusion Cefoperazone - Shubatan as acute exacerbation of chronic obstructive pulmonary disease treatment experience of drug use, good efficacy, mild adverse reactions.
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