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抗精神病药物与血脂、血糖代谢、肥胖的相关性

Correlation between antipsychotics drugs and lipids, glucose metabolism, obesity

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目的:总结分析抗精神病药物对精神病患者的血脂、血糖以及肥胖的影响。方法:选择2010年6月~2012年11月期间我院收治的110例精神病患者为研究对象,均给予抗精神病药物治疗10周,比较治疗前后患者血脂、血糖、肥胖指标的变化情况。结果:110例精神病患者服用抗精神药物治疗后体重(70.5±12.6)kg明显高于治疗前,血糖水平(5.4±0.9)mmol/L、甘油三酯水平(1.8±1.2)mmol/L明显高于治疗前,差异具有统计学意义(P<0.01)。结论:抗精神病药物具有增加精神病患者血糖、血脂代谢的作用,容易引起患者肥胖。
Objective: To investigate impact of antipsychotic drugs on mental patients lipids, blood glucose and the obesity. Methods: 110 cases of patients with psychosis in our hospital from June 2010 to November 2012 were selected as study,treated by antipsychotics drugs for 10 weeks. Changes in blood lipids , blood glucose, obesity indicators before and after treatment were compared. Results: After treatment,the weight(70.5±12.6)kg, blood glucose levels (5.4±0.9) mmol / L , and triglyceride levels (1.8±1.2) mmol / L of 110 patients with psychosis were significantly higher than that of before treatment(P<0.01). Conclusion: Antipsychotics drugs can increase blood sugar , lipid metabolism of psychiatric patients and make patients prone to obesity.

antipsychotics drugslipid metabolismobesitycorrelation

邱松伟、樊素琴

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河南省郑州市第八人民医院 450006

抗精神病药物 血脂代谢 肥胖 相关性

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(5)
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