摘要
目的：探讨阿曲库胺与琥珀胆碱在无抽搐电休克治疗（MECT）中的应用比较。方法选择18-60岁，ASAⅠ-Ⅱ级，无截瘫、烧伤、过敏史、高血钾等器质性疾病的精神分裂症患者60例。随机分为阿曲库铵组（A组20例，阿曲库铵、新斯的明组（B组20例），琥珀胆碱组（C组20例），分别观察注药后肌松药起效时间，MECT后呼吸恢复时间，患者完全清醒时间。结果与A组、B组相比较，C组起效时间、自主呼吸恢复时间均较A组、B组快、短、好（P＜0.05），B组自主呼吸恢复时间较A组快（P＜0.05）。三组患者清醒时间差异无统计学意义(P＞0.05)。结论在无琥珀胆碱情况下，阿曲库铵与新斯的明合用不失为一种可行的 MECT治疗方法。
Abstract
Objective To compare the effect of both atracurium and suxamethonium in moden non-convulsively electuoconvulsive therapy(MECT). Method Sixth mental patients aged from eighting to sixty , ASA Ⅰ~Ⅱexcept for paraplegia ,fire burn, al ergy,hyperkalemia and other organic diseases were randomly divided into 3 groups : atracurium group (group A , n=20), atracurium compound with neostigmine group (group B , n=20) and suxamethonium group (group C , n=20) . Muscle relaxation onset time, breathing recovery time , and awake time were observed respectively. Result Muscle relaxation onset time, breathing recovery time in group C were shorter and better than that in group A and group B(P<0.05) .Awake time among three groups have no significance statistical difference(P﹥0.05). Conclusion Atracurium compound with neostigmine is a good method in moden non-convulsively electuoconvulsive therapy if there has no Auxamethonium.
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