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烟台458例儿童乙肝表面抗体调查分析

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目的:跟踪调查458名按正常免疫接种程序完成乙肝疫苗接种儿童乙肝抗体的产生情况,为预防乙肝提供参考资料。方法:对458名儿童血清采用酶联免疫分析(ELISA)方法检测乙肝抗体的结果进行回顾性统计分析。结果:8月龄时93.6%的儿童乙肝抗体为阳性,而到4周岁时乙肝抗体阳性率仅为19.2%,差异明显。单独接种深圳康泰疫苗的8月龄儿童乙肝抗体阳性率90.9%,4周岁乙肝抗体阳性率12.1%,混合接种8月龄儿童乙肝抗体阳性率91.4%,4周岁乙肝抗体阳性率16.5%,差异无统计学意义。结论:4岁儿童乙肝抗体阳性率较8月龄儿童明显下降,且混合接种不影响乙肝抗体产生效果,及时对抗体阴性儿童及时进行疫苗补种对防治乙肝具有重要意义。
Investigation of surface antibody Yantai 458 cases of children with hepatitis B
Objective: tracked 458 normal immunization program for children to complete the hepatitis B vaccination of hepatitis B antibodies, the reference data for the prevention of hepatitis. Methods: 458 children in serum using an enzyme-linked immunoassay (ELISA) to detect hepatitis B antibody results were retrospectively analyzed. Results: 93.6% of 8-month-old children with hepatitis B antibody positive, and 4 years of age when HBV antibody positive rate was 19.2%, the difference is obvious. Shenzhen Kangtai vaccine inoculation alone 8-month-old children with hepatitis B antibody positive rate of 90.9%, 4 years of hepatitis B antibody positive rate of 12.1%, 8-month-old child mixed hepatitis B vaccination antibody positive rate was 91.4%, 4 years of hepatitis B antibody positive rate of 16.5%, the difference was not statistical y significant. Conclusions: HBV antibody positive rate 4-year-olds decreased significantly compared with 8-month-old child, and the mix of hepatitis B vaccination does not affect antibody production results in a timely manner to the antibody-negative children in a timely manner to replant the prevention of hepatitis B vaccine is important.

Childrenhepatitis B surface antibody

吴丽莉、胡雪梅

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滨州医学院 256600

儿童 乙肝表面抗体

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(7)
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