首页|蒙特利尔认知评估量表对女性抑郁症患者认知功能障碍评估的初步研究

蒙特利尔认知评估量表对女性抑郁症患者认知功能障碍评估的初步研究

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目的:观察北京版蒙特利尔认知评估量表(Montreal Cognitive Assessment Scale,MoCA)对女性抑郁症患者认知功能障碍的评定效果,并对其标准效度进行检验。方法:应用简易智能状态检查量表(Mini-MentalState Examination,MMSE)和MoCA分别对实验组(49例女性抑郁症患者)和对照组(47例健康女性)进行认知功能评估,实验组给予对应临床治疗,并于8周后再次进行MMSE和MoCA评估。结果:对照组和实验组患者治疗前后MoCA与MMSE总分均具有较好相关性(r=0.901, r=0.892,r=0.871,P<0.05)。实验组治疗前后MoCA各分测验得分及总分较对照组有差异,具有统计学意义(P<0.05),实验组患者治疗后8周,除延迟记忆、抽象、视空间执行功能外,较治疗前MoCA各分测验得分及总分明显提高,具有有统计学意义(P<0.05)。实验组治疗前MoCA检出率明显高于MMSE检出率,差异有统计学意义(χ2=5.63,P<0.05)。结论:MoCA在临床中筛查女性抑郁症患者的认知功能障碍具有可靠的标准效度,与MMSE比较,MoCA对于筛查女性抑郁症患者的认知功能障碍有较好的敏感性。
Purpose:Observe the Beijing edition of the Montreal Cognitive Assessment (Montreal Cognitive Assessment Scale, MoCA) on cognitive dysfunction in female patients with depression assessment results, and to test the validity of its standards.Method:applications Mini Mental State Examination Scale(Mini-MentalState Examination,MMSE),and MoCA were the experimental group(49 cases of women with depression) and control group (47 cases of healthy women) to assess cognitive function,corresponding to the experimental group were given clinical treatment and at 8 weeks after the MMSE and MoCA assessment again.Results:The patients in the control group and the experimental group before and after treatment MoCA and MMSE scores were correlated with good (r = 0.901,r=0.892,r=0.871,P<0.05).MoCA experimental group before and after treatment, and the total score for each subtest score differences compared with the control group, with statistical significance (P<0.05), patients in the experimental group after 8 weeks of treatment,in addition to delay edmemory,abstraction,visuos patial executive function,compared with treatment MoCA before each subtest scores and total scores improved significantly,with a statistical y significant (P<0.05).Before treatment, the experimental group was significantly higher detection rate MoCA MMSE detection rate. The difference was statistical y significant (χ2=5.63,P<0.05).Conclusion: MoCA screening women for depression in patients with cognitive dysfunction in clinical standards with reliable validity, compared with the MMSE, MoCA screening women for depression in patients with cognitive dysfunction have better sensitivity.

杨旻实

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沈阳市精神卫生中心 110168

女性 抑郁症 认知功能 蒙特利尔认知评估量表 简易智能状态检查量表

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(7)
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