Objective: to investigate the brain surgery in patients with critical patients blood sugar control method and the corresponding nursing measures. Selection methods: from January 2013 to January 2013 in our hospital and was diagnosed with brain income 30 cases of severe craniocerebral injury patients, al patients were performed after the 24 hours after injury glucose determination, determination of glucose to avoid input, 8 hours before patients after 24 hours after injury of different levels of blood sugar to rise. Take the blood glucose monitoring in patients with 30 cases, blood sugar control, and comprehensive nursing measures, the blood sugar recovery were observed. Results: 30 cases of patients except two cases of blood glucose in patients with cerebral hernia has not improved, 4-14 days in 12 patients had returned to normal blood sugar, blood glucose in 14 days after the rest of the 16 patients return to normal levels. Conclusions: the brain critical patients and patients with abnormal blood sugar, blood sugar monitoring in time, to control blood sugar, coupled with comprehensive nursing intervention can effectively control the patient's blood sugar, prevent the patient from further deterioration.