脂肪母细胞瘤和脂肪母细胞瘤病临床病理分析(附2例报告)
娜仁 1凡琳琳 1李乾 1卢玉娟1
作者信息
摘要
脂肪母细胞瘤(lipoblastoma)和脂肪母细胞瘤病(lipoblastomatosis)为少见的儿童软组织良性肿瘤。Jaffe于1924年首先使用。lipoblastoma描述为未成熟脂肪细胞的肿瘤。Vel ios等人于1958年使用lipoblastomatosis描述新生儿脂肪组织内良性新生物。其后陆续有个案报道,并总结出其生物学行为特征。肿瘤局限于局部者称脂肪母细胞瘤;病变弥漫且向周围组织或肌肉浸润者称脂肪母细胞瘤病(lipoblastomatosis)[1]。本文报道脂肪母细胞瘤2例,通过探讨其临床表现、组织学形态、免疫学表型以及鉴别诊断,进而促进对此种少见肿瘤的认识,避免误诊误治。
Abstract
Lipoblastoma and lipoblastomatosis is a rare kind of benign soft tissue tumors for children. Jaffe was the first to use in 1924. Lipoblastoma was described as solid tumors of immature fat cel s. Vel ios, etc. used it to define a newborn new creatures in the benign fatty tissues in 1958. More cases ware reported subsequently and sumed up its biological behavior characteristics. Tumor confined to localization cal lipoblastoma; and those infiltrating to the surrounding tissue cal lipoblastomatosis [1]. This paper reports 2 cases of lipoblastoma by exploring its clinical manifestations, histological morphology, immunophenotype and differential diagnosis, thus to promoting awareness of this rare tumor to avoid misdiagnosis.
关键词
脂肪母细胞瘤/脂肪母细胞瘤病/诊断/鉴别诊断Key words
lipoblastoma/lipoblastomatosis/diagnosis/Differential diagnosis引用本文复制引用
出版年
2014