Objective:To investigate and analyze the clinical efficacy of adefovir in the treatment of chronic hepatitis B(CHB).Methods:93 CHB patients in our hospital from June 2012 to September 2013 were randomly divided into adefovir group (experimental group) and lamivudine group (control group),adefovir and lamivudine were given in two groups respectively,efficacy of two groups after treatment were compared.Results:Changes of ALT,AST and HBV-DNA after 12,24,48 weeks of treatment in experimental group were more significant than control group,difference was statistical y significant (p<0.05),transfer situation of HBV-DNA,HBeAg/anti-HBe of experimental group was better than control group,difference was statistical y significant (p<0.05),Conclusion:Efficacy of adefovir in the treatment of CHB is significant,which deserves to be promoted inclinic.
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