acinetobacter baumanni is currently one of the most important pathogens of nosocomial infection, serious influence patient's life. Acinetobacter baumanni special genetic structure, leading to its high resistance for a variety of clinical antibiotics, the infection when limited selection of drugs, and clinical curative effect is relatively poor. Therefore, the present stage must be explicitly acinetobacter baumanni resistant mechanism, choose reasonable and effective antibiotics, and adjust the treatment according to the results of the drug susceptibility. Mechanism of drug resistance of acinetobacter baumanni mainly resistant enzyme production, the change of drug action, the formation of drug efflux pump ", and the outer membrane protein structure and quantity change and integration of sub structures and genetic changes. Clinical doctors should clear acinetobacter baumanni for al kinds of drug resistant mechanism, timely grasp the region of acinetobacter baumanni epidemic characteristics and drug resistance, reasonable use of antibiotics, and the note in patients' sputum, to control the infection rate of the drug resistant strains.
acinetobacter baumanniDrug resistance mechanismEvolution to investigate
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