Objective: To investigate the screening effect of pepsinogenⅠ (PGⅠ) and epsinogenⅡ(PGⅡ) detection on gastric ulcer patients. Methods: 2052 physical examination population and 120 gastric ulcer patients were selected for PGⅠand PGⅡ detection in XXX hospital,from January 2011 to October 2011. Results: Serum PGⅠ, PGⅡ, and PGⅠ/PGⅡ in physical examination population were 316.7±129.2ng/ml, 40.2±30.1ng/ml, and 12.0±4.9, respectively. Each was significantly higher than those in gastric ulcer patients (156.0±63.8ng/ml, 5.9±11.1ng/ml, and 9.7±4.3,respectively.)(P<0.05). If PGⅠ<270.9 ng/ml as a reference, Positive expectations to gastric ulcer was 61.7%; PGⅡ<37.8ng/ml as a reference, Positive expectations to gastric ulcer was 55.8%; PGⅠ/PGⅡ<14.4 as a reference, Positive expectations to gastric ulcer was 13.3%. Conclusion: Serum PGⅠ and PGⅡ in gastric ulcers was significantly higher than those in physical examination population. Therefore, they may be useful in screening of gastric ulcer patients in large populations.
NETL
NSTL
万方数据
