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鼻咽癌常规放疗中电子线L形野照射技术应用研究

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目的探讨电子线L形野照射技术用于鼻咽癌常规放疗中射野之间衔接的问题。方法回顾我院在2011年04月至2013年10月住院治疗的120例鼻咽癌患者,随机分成观察组和对照组,每组各60例,观察组的布野使用三维计划系统,在系统中模拟鼻咽癌2D-适形放疗(CRT)或3D-CRT治疗中电子线L形野照射技术,对照组则使用常规颈后电子线野照射技术进行布野,所有患者放疗过程中均需记录各个区域的照射剂量。结果两组120例鼻咽癌患者均完成放射治疗,其中观察组和对照组的的靶区剂量的包绕体积超过6000cGy剂量的达到95%以上,符合临床上治疗肿瘤的剂量,但对照组(颈后电子线野照射技术)患者出现明显的剂量热点,平均剂量高达8700±360cGy,而观察组(电子线L形野照射技术)平均剂量为6500±290cGy,两组相比较,差异具有显著性,P<0.05;观察组(电子线L形野照射技术)咽喉部剂量超过6500cGy的平均包绕体积只有17.32±3.12%,而对照组(颈后电子线野照射技术)却高达37.83±5.39%,两组相比较,差异具有显著性,P<0.05。结论观察组(电子线L形野照射技术)在临床上治疗肿瘤的剂量需要与对照组(颈后电子线野照射技术)相比差异无显著性,P>0.05,但观察组(电子线L形野照射技术)在照射野之间的衔接和剂量均匀分布方面具有明显的优势,且安全有效,值得临床推广应用。
Objective To investigate the electronic line L-shaped field irradiation technique for convergence between conventional radiotherapy in nasopharyngeal radiation field problems . Methods in our hospital from April 2011 to October 2013 120 hospitalized patients with nasopharyngeal carcinoma were randomly divided into observation group and control group , 60 cases in each group ,the observation group planning system using three-dimensional simulation of 2D-nasopharyngeal conformal radiotherapy (CRT) ,or 3D-CRT treatment L -shaped electron beam irradiation techniques cloth wild wild, neck control group using conventional electron beam irradiation techniques cloth wild wild, al patients during radiotherapy dose required to record each region .Results There were 120 cases of nasopharyngeal carcinoma patients completed radiation therapy , in which the target dose observation group and the control group were more than 6000 cGy of enveloping volume has reached more than 95%,to meet the needs of the clinical dose of cancer treatment ,but control group (neck electron beam irradiation technology field) dose in patients with significant hot spots , the average doses up to 8700±360cGy, while the observation group (e-Line L-shaped field irradiation technique) average dose of 6500±290 cGy, compared the two groups ,the differences significant,P<0.05; observation group (L-shaped electron beam irradiation technology field ) surrounding the larynx doses greater than average volume of 6500 cGy is only 17.32±3.12%, while the control group (posterior electron beam irradiation technology field) was as high as 37.83±5.39%, compared with the two groups,the difference was significant,P<0.05. Conclusion observation group (E-Line L-shaped field irradiation technique) in the clinical dose cancer therapy requires no significant difference, P>0.05 with the control group (posterior electron beam irradiation technology field) compared with the observation group ,but (electronic line L shaped field irradiation technique) convergence between the radiation field and dose distribution has obvious advantages, and safe and effective , worthy of clinical application.

胡娟、杨睿、常发兴、周嵩

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四川省成都市第五人民医院 611130

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(10)
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