Objective: To evaluate left ventricular synchronicity with hypertrophic cardiomyopathy by real-time three-dimensional echocardiography. Methods: There were 31 HCM patients (upper interventricular septum hypertrophy without left ventricular outflow obstruction) with normal liver and kidneys without endocrine disease, immune system disease and other heart diseases like hypertension, coronary artery disease, congenital heart disease, rheumatic heart disease and arrhythmia. Al the HCM patients were asymptomatic and hadn’t received any clinical treatment yet. 30 normal persons were selected after interrogation enquiry, physical examination, ECG, chest X-ray and echocardiography. Al the patients were checked between October 2012 and May 2013 in affiliated zhongshan hospital of Dalian university. Left ventricular ejection fraction (LVEF), Tmsv16 SD, and Tmsv16 SD* were detected by X3-1 probe, 4 chamber apex view using real-time three-dimensional echocardiography.Results: 1. There was no difference between HCM team and normal team in LVEF(P>0.05).2. Tmsv16 SD、Tmsv16 SD* increased in HCM team and there was significant difference between the two teams(P<0.05).Conclusion: Left ventricular synchronicity decreased in HCM patients without symptoms when LVEF is normal.
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