摘要
目的探讨米非司酮配伍米索前列醇用于终止瘢痕子宫妊娠失败的影响因素。方法回顾性收集我院2008年1月到2013年12月间使用米索终止瘢痕子宫早期妊娠的病例182例,分为完全流产组、流产失败组,比较两组相关影响因素的差异。结果182例瘢痕子宫早期妊娠流产病例,成功率为84.62%(154/182)。子宫位置(后倾、后倾后屈),妊娠周数(>4周),孕次(≥3次),流产史(≥1次),孕囊直径(≥20 mm)者,药物流产失败率明显增高。结论影响药物流产的效果的因素较多,临床实践中应严格掌握适应证和禁忌证,提高药物流产成功率。
Abstract
Objective: The aim of this study was to analyze the influential factors of terminating early pregnancy of scar uterus with mifepristone and misoprostol. Methods: 182 pregnant women were recruited from the sixth people's hospital of Panzhihua between January 2008 and December 2013, screening al women undergoing medical abortion with mifepristone and misoprostol. The clinical outcome was defined as complete expulsion of intrauterine contents without (successful group) or with (failed group) surgical intervention.Results:154 cases were success complete abortion, the rate of complete abortion was 84.62%(154/182). Factors associated with complete abortion were the uterus position (backward, backward after flexor), gestational age (>4 weeks), increased gravidity (≥3), previous abortions (≥1) and gestational sac diameter (≥20mm) were associated with unsuccessful medical abortions.Conclusion: The uterus position, gestational age and history of abortions, gravidity are at increased risk for failed medical abortion.