Objective to explore the comprehensive intervention measures to prevent or delay the progress of diabetes abnormal glucose tolerance. Methods analysis of the control theory principle of progress for diabetes, abnormal glucose tolerance and summarizes the effective measures for comprehensive intervention. Results the comprehensive intervention measures can make the most of the glucose tolerance abnormal to normal glucose tolerance, and delay the development of abnormal glucose tolerance largely for diabetes. Conclusion comprehensive intervention treatment, can make more abnormal glucose tolerance back to normal blood sugar, reduce to diabetes, and can protect blood vessels, reduce complications, reduce the risk of cardiovascular events.