摘要
目的：分析对双相障碍躁狂发作患者临床采取阿立哌唑联合丙戊酸钠进行治疗的疗效。方法：选取我院近来3年收治的双相障碍躁狂发作患者100例，随机分为AB两组，其中A组采取阿立哌唑联合丙戊酸钠方案进行治疗，B组采取奎硫平联合丙戊酸钠方案进行治疗，对比两组患者的临床疗效。结果：A组患者的总有效率显著高于B组，其不良反应发生率明显小于B组，差异存在统计学意义（P<0.05）。另外，AB两组患者经过治疗后，其BRMS评分均有所下降，A组下降程度明显大于B组，差异存在统计学意义（P<0.05）。结论：对双相障碍躁狂发作患者临床使用阿立哌唑联合丙戊酸钠治疗，效果显著，不良反应发生率小，起效时间快，值得各大医院临床推广使用。
Abstract
Objective: to analyze clinical patients with bipolar disorder manic state o take pp azole joint valproate treatment curative effect. Methods: our hospital in recent 3 years were analyzed in 100 patients with bipolar disorder manic, randomly divided into AB in the two groups, one group A state o take pp azole joint valproic acid sodium solution treatment, group B to quetiapine combined valproic acid sodium solution treatment, compared the clinical efficacy of two groups of patients. Consequence: the total effective rate in group A patients was significantly higher than that of group B, the incidence of adverse reactions are much smal er than group B, the difference is statistical y significant (P<0.05). In addition, AB two groups of patients after treatment, the BRMS scores were decreased, decline in group A was significantly greater than group B, the difference is statistical y significant (P<0.05). Conclusion: the clinical use in patients with bipolar disorder manic state o pp azole joint valproate treatment, the effect significantly, the incidence of adverse reactions, working time is fast, is worth popularizing hospitals for clinical use.
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