首页|41例合并甲状腺功能亢进症重症肌无力患者的临床特点分析

41例合并甲状腺功能亢进症重症肌无力患者的临床特点分析

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目的:探究重症肌无力合并甲状腺功能亢进的临床特点。方法:回顾分析2009年3月-2014年4月到我院神经科治疗重症肌无力且同时伴有甲状腺功能亢进的41例患者的相关检测和治疗情况,采用相关计算机软件进行记录、统计和分析,作出数据对比。结果:检测患者血清乙酰胆碱受体抗体,39例阳性,P/N≥2.0;采用放射免疫分析法检查患者三碘甲状腺原氨酸(T3)、甲状腺球蛋白抗体(TGAb)、甲状腺素(T4)和抗甲状腺微粒抗体(TMAb),4种指标均高于正常值;术前胸部进行C T检查,结果显示:胸腺增生11例、胸腺瘤2例、胸腺未见异常者3例。结论:重症肌无力常合并其它自身免疫性疾病,特别是甲状腺功能亢进症、胸腺增生等,疾病间的相关性还有待进一步研究。
Objective: Myasthenia Gravis explore the clinical features of hyperthyroidism.Methods: Retrospective analysis of correlation detection and treatment in June 2009 -2014 April to hospital neurology treatment of myasthenia gravis and hyperthyroidism accompanied by 41 patients, Using the relevant computer software for recording, Statistics and analysis, making data comparison. Results: Detection of serum acetylcholine receptor antibodies, 39 cases of positive,P / N ≥ 2.0; using radioimmunoassay check the patient three tri odothyronine (T3), Thyroglobulin antibody (TGAb), Thyroxine (T4) and anti-thyroid microsomal antibodies (TMAb), Four kinds of indicators are higher than normal; Preoperative chest CT examination, The results showed that: thymic hyperplasia in 11 cases, 2 cases of thymoma, thymic abnormalities seen in 3 patients. Conclusion: Myasthenia gravis is often associated with other autoimmune diseases, Remains to be further studied the correlation between the disease.

Myasthenia gravisHyperthyroidismAcetylcholine receptor antibodyClinical features

郑远征、高峰、王金兰、朱明振、张迎娜

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郑州大学第二附属医院神经内科 河南郑州 450000

郑州大学医药科学研究院 < 郑州市神经免疫学重点实验室 > 河南郑州 450000

重症肌无力 甲状腺功能亢进 乙酰胆碱受体抗体 临床特点

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(17)
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