Obejective To evaluate the effect and toxicity of S1 combined with low dose Docetaxel in patients of advanced gastric cancer .methods Twenty patients of advanced gastric cancer were treated with combination therapy of S1 60mg bid on days 1 through 14 plus Docetaxel 40mg/m2 day 1,every 21 days.The evaluation of efficacy and toxicity was achieved in performed after every 2 cycles .Resuit Al 20 patients assessed for efficacy and toxicity. The disease control was 40%,The common toxicities of the regimen included myelosuppression and gastrointestinal reactions.Conclusions The regimen of S1 plus Docetaxel is effective against advanced gastric cancer with acceptable toxicity.
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