Objective To explore the predicting value of neutrophil-lymphocyte ratio in coronary thrombus formation of non-ST-segment elevated acute coronary syndrome (NSTEACS). Methods Whole blood leukocytes(WBC), neutrophil and lymphocyte percent(Neu and Ly) were measured in 142 patients with NSTEACS, 80 patients with stable angina pectoris(SAP), and 50 healthy volunteers.The Neutrophil-lymphocyte ratio (NLR) was calculated. And patients with NSTEACS were assigned into two groups including group thrombosis and group non-thrombosis, the sensitivity, specificity, positive predicting value, and negative predicting value were calculated,too.Final y, the receiver operating characteristic (ROC) curve was used to evaluate the diagnostics efficacy of al indicators. Results At group NSTEACS, levels of WBC, Neu and NLR were significantly higher,but Ly was significantly lower than that at group SAP and group healthy volunteers(P<0.001). At group thrombosis , level of Ly <br> was notably lower, but levels of other indicators and positive rates of al indicators ware remarkably higher than that at group non-thrombosis(P<0.01).At group thrombosis, the positive rate of NLR was the highest in al indicators. Compared with others, the sensitivity and positive predicting value of NLR was the highest for coronary thrombus formation, and the area under curve of ROC was 0.887,95%CI(0.822-0.913) ,which was more higher than that of other indicators. The cutoff value of NLR was 2.88, and the sensitivity, specificity, positive predicting value, and negative predicting value were 94.2 %、75.0%、85.3% and 89.4%,respectively. Conclusion NLR can be used as the sensitive and practical indicator to predict the coronary thrombus formation of patients with non-ST-segment acute coronary syndrome.
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