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影响肝硬化食管静脉曲张出血急诊药物疗效的因素分析

Bleeding esophageal varices in cirrhosis emergency affecting drug efficacy factor analysis

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目的::探讨影响肝硬化食管静脉曲张出血急诊药物疗效的因素。方法:选择我院2009年1月~2012年2月收治的肝硬化食管曲张静脉出血住院的患者85例,选择生长抑素(14肽或8肽)或者垂体后叶素进行急诊治疗,记录有可能出现的影响急诊血管活性药物效果的因素,并作相关性分析。结果:止血成功率为69.41%,其中肝功能Child分级(P<0.05),止血成功组出血程度(P<0.05), PLT (P<0.05),PT( P<0.05), PTA(P<0.05), ALB (P<0.05)同止血失败组比较,差异具有统计学意义,其中出血的程度(OR=26.87)和Child分级(OR=48.65)为影响血管活性药物的治疗疗效的最主要因素。结论:通过肝功能Child分级和出血程度可以预测血管活性药物治疗成功率的关键因素。改善PTA和PT对急诊止血和预防再出血均有一定帮助。
Objective To investigate the effects of bleeding esophageal varices in cirrhosis emergency drug efficacy factor. Methods In our hospital in January 2009 ~ February 2012 admitted variceal bleeding in cirrhotic patients hospitalized with 85 cases, select somatostatin (14 peptides or 8 peptide) or vasopressin for emergency treatment, the records may Emergency influence appearing factors effect of vasoactive drugs, and for correlation analysis. Results Hemostasis success rate of 69.41%, including liver function Child classification (P <0. 05), the degree of bleeding hemostasis success group (P <0.05), PLT (P <0. 05), PT (P <0. 05), PTA (P <0. 05), ALB (P <0. 05) with failure to control bleeding group, the difference was statisticaly significant, including the extent of bleeding (OR = 26.87) and the Child classification (OR = 48.65) for the effect of vasoactive therapeutic efficacy of the most important factors. Conclusion Child classification of liver function and bleeding can predict treatment success rate of vasoactive drugs a key factor. PTA and PT on improving emergency hemostasis and prevent rebleeding have some help.

CirrhosisEsophageal varicesDrugsEfficacy

蒋明勇、李佳、肖世元

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四川省岳池县人民医院急诊科 四川岳池 638300

四川省绵阳市中医院急诊科 四川绵阳 621000

肝硬化 食管静脉曲张 药物 疗效

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(20)
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