Objective To investigate the effects of bleeding esophageal varices in cirrhosis emergency drug efficacy factor. Methods In our hospital in January 2009 ~ February 2012 admitted variceal bleeding in cirrhotic patients hospitalized with 85 cases, select somatostatin (14 peptides or 8 peptide) or vasopressin for emergency treatment, the records may Emergency influence appearing factors effect of vasoactive drugs, and for correlation analysis. Results Hemostasis success rate of 69.41%, including liver function Child classification (P <0. 05), the degree of bleeding hemostasis success group (P <0.05), PLT (P <0. 05), PT (P <0. 05), PTA (P <0. 05), ALB (P <0. 05) with failure to control bleeding group, the difference was statisticaly significant, including the extent of bleeding (OR = 26.87) and the Child classification (OR = 48.65) for the effect of vasoactive therapeutic efficacy of the most important factors. Conclusion Child classification of liver function and bleeding can predict treatment success rate of vasoactive drugs a key factor. PTA and PT on improving emergency hemostasis and prevent rebleeding have some help.