首页|影响肝硬化食管静脉曲张出血急诊药物疗效的因素分析

影响肝硬化食管静脉曲张出血急诊药物疗效的因素分析

扫码查看
目的::探讨影响肝硬化食管静脉曲张出血急诊药物疗效的因素。方法:选择我院2009年1月~2012年2月收治的肝硬化食管曲张静脉出血住院的患者85例,选择生长抑素(14肽或8肽)或者垂体后叶素进行急诊治疗,记录有可能出现的影响急诊血管活性药物效果的因素,并作相关性分析。结果:止血成功率为69.41%,其中肝功能Child分级(P<0.05),止血成功组出血程度(P<0.05), PLT (P<0.05),PT( P<0.05), PTA(P<0.05), ALB (P<0.05)同止血失败组比较,差异具有统计学意义,其中出血的程度(OR=26.87)和Child分级(OR=48.65)为影响血管活性药物的治疗疗效的最主要因素。结论:通过肝功能Child分级和出血程度可以预测血管活性药物治疗成功率的关键因素。改善PTA和PT对急诊止血和预防再出血均有一定帮助。
Bleeding esophageal varices in cirrhosis emergency affecting drug efficacy factor analysis
Objective To investigate the effects of bleeding esophageal varices in cirrhosis emergency drug efficacy factor. Methods In our hospital in January 2009 ~ February 2012 admitted variceal bleeding in cirrhotic patients hospitalized with 85 cases, select somatostatin (14 peptides or 8 peptide) or vasopressin for emergency treatment, the records may Emergency influence appearing factors effect of vasoactive drugs, and for correlation analysis. Results Hemostasis success rate of 69.41%, including liver function Child classification (P <0. 05), the degree of bleeding hemostasis success group (P <0.05), PLT (P <0. 05), PT (P <0. 05), PTA (P <0. 05), ALB (P <0. 05) with failure to control bleeding group, the difference was statisticaly significant, including the extent of bleeding (OR = 26.87) and the Child classification (OR = 48.65) for the effect of vasoactive therapeutic efficacy of the most important factors. Conclusion Child classification of liver function and bleeding can predict treatment success rate of vasoactive drugs a key factor. PTA and PT on improving emergency hemostasis and prevent rebleeding have some help.

CirrhosisEsophageal varicesDrugsEfficacy

蒋明勇、李佳、肖世元

展开 >

四川省岳池县人民医院急诊科 四川岳池 638300

四川省绵阳市中医院急诊科 四川绵阳 621000

肝硬化 食管静脉曲张 药物 疗效

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(20)
  • 4