Objective The Observation of clinical efficacy on Infantile viral enteritis treated by different drugs.Methods 198 cases which were testing positive by stool rotavirus antigen were randomly divided into three groups(control group,the Reduning treatment group,the glucose octyl treatment group),and observed effects.Results Compare the efficacy of two-drug treatment group and control group,there were statisticaly differences(p<0.05), but no significant difference between two treatment group.Conclusion Reduning injection in the treatment of children with rotavirus enteritis with significant effect and is worthy of further clinical research applications; the Glucose octyl simple auxiliary treatment of diarrhea is worthy of promotion.