objective to improve the level of the diagnosis and treatment of pregnancy with acute appendicitis, reduce fetal mortality. Methods retrospective analysis the clinical data of 25 cases of pregnancy with acute appendicitis. The results of diagnosis and treatment of delayed 3 cases, 2 cases of abortion, 22 cases of timely diagnosis and treatment of pregnancy. Conclusion timely and correct the diagnosis of pregnancy with acute appendicitis, surgical intervention is the key to reduce the risk of maternal and infant.