objective to explore the etiology and clinical treatment of patients with chronic cough. Methods 58 cases of patients with chronic cough according to cough process inspection diagnosis analysis, according to diagnosis, according to different causes different treatment methods. Results this group of patients cough reason clear diagnosis, unknown reason, 12.07%, 87.93% of cough variability asthma (25.86%), nose and throat diseases cause cough (20.69%). Clinical treatment according to different causes and different treatment methods, treatment effective rate was 94.83%. Conclusion emphasis on early diagnosis and early treatment of chronic cough, is to improve the treatment effect and quality of life of patients with effective methods.