objective: to study the nursing risk management in the application of urology endoscopic surgery effect. Methods: analyze the problems existing in the urology surgery, and targeted for risk management. Results: after given specification of risk management, surgical instrument preparation, equipment management, nursing staff technology level and disinfection measures scores were significantly higher than those before the implementation, and nursing satisfaction rate increased significantly, P<0.05 compared with difference was statisticaly significant. Conclusion: to establish a perfect risk management system, and take effective measures to prevent and reduce risk occurs, which can effectively improve the quality of clinical nursing.