To explore the Predicting Value of Serumβ-HCG levels and Progesterone in the Treatment of in Ectopic pregnancy(EP) after conservative treatment .Methods:142 patients were submitted to the systemic medical treatment.Al conservative <br> treatment patients were treated with multidose of MTX and Ru486 .The serum levels ofβ- HCG and Progesterone <br> were detected before treatment and on day4, 7,14 after the therapy. Results β-HCG levels was positively correlated <br> with Progesterone levels before treatment. ( spearman correlation).Whether conservative treatment was successful or not was related with β-HCG levels and Progesterone levels, Especialy blood HCG and progesterone level variation after 7 days of drug treatment. Conclusion: β-HCG ang Progesterone values may be the important reference indexes to predict whether conservative treatment success or not.