Immunology is a biomedical science which studies on the immune response to antigenic material of organisms and the method. It has achieved great progress applying in infectious diseases.This article discusses the three aspects of immune regulatory network, cytokines and immunomodulators. The immune regulatory network provides a new perspective of prevention and cure of infectious diseases. Cytokines and cytokine inducer can activate the immune response mechanism in vivo to resist pathogens. Synthetic and vegetable immunomodulators has also achieved satisfactory results for anti-infection in clinical. Immunology are widely used and its development wil bring new hope for human health.