摘要
清醒气管插管是临床工作中处理困难气道的常用方式，恰当使用镇痛镇静药物是保证插管成功的重要辅助手段。右美托咪定是一种高效和高选择性的α2肾上腺素能受体激动剂，具有镇静镇痛、抑制交感神经活性、抑制炎症反应、心肌保护、抑制应激相关的恐惧记忆和学习等作用。现就上述作用在清醒气管插管中的应用及相关的研究进展进行综述。
Abstract
Awake tracheal intubation is a common way to difficult airway in clinical work, the appropriate use of analgesic and sedative drugs is an important supplementary means of successful intubation. Dexmedetomidine is a kind of high efficient and high selective α2 adrenergic receptor agonist, with sedation and analgesia, restraining the activity of sympathetic nerve, inhibiting the inflammatory reaction, myocardial protection, restraint stress related fear memory and learning effect, this article reviews the progress in the application in the awake tracheal intubation and related research.
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