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利培酮治疗老年精神障碍的疗效及安全分析

Risperidone curative effect and safety analysis for the treatment of elderly mental disorders

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目的:对利培酮治疗老年精神障碍的疗效以及安全性进行观察和分析。方法:此次临床研究主要以我院在2009年5月份到2013年5月份收治的100例老年精神障碍患者为研究对象。采用随机分配的原则,将所有患者分成对照组和实验组,每个组别各50例。对照组主要实施奋乃静治疗,实验组患者主要实施利培酮治疗。对两组患者的临床疗效以及安全性进行观察和比较。结果:经临床研究结果显示,实验组患者临床总有效率与对照组差异不存在统计学意义, P>0.05;实验组患者的不良反应发生率明显小于对照组,差异存在统计学意义,P<0.05。结论:经临床研究结果表明,使用利培酮对老年精神障碍进行治疗,具有较好的疗效,且安全性好,值得推广和普及。
Objective: for the treatment of risperidone elderly mental disorders of observation and analysis on the efficacy and safety. Methods: the clinical study mainly in our hospital in May 2009 to May 2013 treated 100 cases of elderly patients with mental disorder as the research object. Based on the principle of random distribution, al patients were divided into control group and experimental group, 50 cases each group. Control the main implement perphenazine therapy, the main implementation of risperidone treatment. On two groups of patients with clinical efficacy and safety were observed and compared. Results: clinical research results show that the experimental group patients clinical total effective rate and the control group, there is no statistical y significant difference, P > 0.05; The experimental group the incidence of adverse reactions of patients is lower than the control group, the difference is statistical y significant,P<0.05). Conclusion: the clinical research results show that using risperidone treatment of elderly mental disorders, has good curative effect, safety and good, worthy of promotion and popularization.

risperidoneElderly mental disordersCurative effectsecurity

张廷柱

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吉林省公安厅安康医院 136100

利培酮 老年精神障碍 疗效 安全

2014

中外健康文摘
中国中医药报社

中外健康文摘

影响因子:0.016
ISSN:1672-5085
年,卷(期):2014.(27)
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