Objective:The foreign expert group on Burn Rehabilitation published the practice guidelines for pain management and sedation during wound care in Children with Burns in September 2022,the guidelines provides evidence-based recommenda-tions on pain management and sedation in the process of wound care for children with burns,including pain assessment,pain management and surgical analgesia and sedation.This article focuses on the interpretation of the guidelines,aiming at making clinical medical staff understand the new progress of pain management and sedation in the process of wound care of children with burns,and providing evidence-based guidance and suggestions for clinical practice.