摘要
目的:分析彩色多普勒超声(CDU)诊断乳腺癌的价值.方法:选取2020年7月至2023年7月本院收治的64例乳腺病变患者,所有患者均行CDU,以病理检查为"金标准",分析CDU诊断乳腺癌的价值,另分析不同性质乳腺病变的超声血流参数差异.结果:64例乳腺病变患者,病理检查共检出15例恶性,49例良性;以病理检查为"金标准",CDU诊断乳腺癌的灵敏度为86.67％(13/15)、准确度为 95.31％(13+48)/64、特异度为 97.96％(48/49)、阳性预测值为 92.86％(13/14)、阴性预测值为 96.00％(48/50);kappa检验显示,CDU的检查结果与"金标准"的检查结果一致性极好(kappa值=0.866,P=0.000);恶性乳腺病变的搏动指数(PI)为(1.29 ±0.35)、阻力指数(RI)为(0.97±0.15)、收缩期峰值血流速度(PSV)为(12.49±2.36)cm/s,形态不规则占比为80.00％(12/15)、边界不清占比为73.33％(11/15)、有钙化占比为66.67％(10/15)、血流丰富占比为86.67％(13/15)、回声不均占比为80.00％(12/15),高于良性乳腺病变的(1.01±0.24)、(0.72±0.06)、(8.71±1.54)cm/s、26.53％(13/49)、30.61％(15/49)、16.33％(8/49)、18.37％(9/49)、22.45％(11/49),差异有统计学意义(P＜0.05).结论:CDU能够有效诊断出乳腺癌,通过超声血流参数可进一步鉴别诊断出乳腺癌,具有一定的诊断价值,临床应用价值较高.
Abstract
Objective:To analyze the value of color Doppler ultrasonography(CDU)in the diagnosis of breast cancer.Methods:64 patients with breast lesions admitted to our hospital from July 2020 to July 2023 were selected,all of whom underwent CDU.The value of CDU in the diagnosis of breast cancer was analyzed with pathological examination as the"gold standard",and the differences in ultrasound blood flow parameters of breast lesions of different nature were also analyzed.Results:Of the 64 patients with breast lesions,15 were malignant and 49 were benign.Using pathological examination as the"gold standard",the sensitivity of CDU in the diagnosis of breast cancer was 86.67％(13/15),the accuracy was 95.31％(13+48)/64,the speci-ficity was 97.96％(48/49),the positive predictive value was 92.86％(13/14),and the negative predictive value was 96.00％(48/50).kappa test showed that the results of CDU were in good agreement with those of gold standard(kappa value=0.866,P=0.000).The pulsatile index(PI)of malignant breast lesions is(1.29±0.35),the resistance index(RI)is(0.97±0.15),the peak systolic blood flow velocity(PSV)is(12.49±2.36)cm/s,the proportion of irregular morphology is 80.00％(12/15),the proportion of unclear boundaries is 73.33％(11/15),the proportion of calcification is 66.67％(10/15),the proportion of rich blood flow is 86.67％(13/15),and the proportion of uneven echoes is 80.00％(12/15),The rates of(1.01±0.24),(0.72±0.06),(8.71±1.54)cm/s,26.53％(13/49),30.61％(15/49),16.33％(8/49),18.37％(9/49),and 22.45％(11/49)were higher than those of benign breast lesions(P＜0.05).Conclusion:CDU can effectively diagnose breast cancer,and ultrasound blood flow parameters can further differentiate the diagnosis of breast cancer,which has certain diagnostic value in clinical application.
维普
万方数据