Research progress of anti-HER2 breast cancer ADC drugs
The incidence of breast cancer ranks first among female malignant tumors,which is due to the uncontrolled prolifer-ation of breast epithelial cells,and then malignant transformation.In the treatment of breast cancer,the application of anti-hu-man epidermal growth factor receptor 2(HER2)breast cancer antibody drug conjugate(ADC)has been paid more and more at-tention,in this paper,the anti-HER2 breast cancer ADC drugs commonly used in the treatment of breast cancer(enmetrastu-zumab,trastuzumab,trastuzumab,trastuzumab dokamazin,vidicetuzumab,MM-302,XMT-1522,ARX788,MEDI4276)were reviewed in order to provide reference for the rational application of anti-HER2 breast cancer ADC drugs.
Breast cancerHuman epidermal growth factor receptor 2Antibody-drug conjugateEnmetrastuzumab