The effect of combined use of phloroglucinol and progesterone injection on pregnancy outcomes in patients with threatened miscarriage
Objective:To observe and analyze the effects of the use of injection of phloroglucinol and progesterone on pregnancy outcomes in patients with threatened miscarriage.Methods:A 2-year study was carried out in Lijin County Maternal and Child Health Hospital,starting from March 2022 and ending in February 2024.110 patients with threatened miscarriage were select-ed as the sample subjects,and were divided into two groups according to different treatment methods:the control group(n=55)and the observation group(n=55),receiving progesterone injection,progesterone injection and phloroglucinol,respective-ly.Compare the time of symptom relief,uterine artery blood flow parameters,progesterone levels and pregnancy outcomes be-tween two groups.Results:1)After the combined application of phloroglucinol and progesterone injection,the relief time of various symptoms in the observation group was shorter than that in the control group,P<0.05.2)The levels of various pa-rameters of uterine artery blood flow in the observation group were lower than those in the control group,P<0.05.3)The levels of various progesterones in the observation group were higher than those in the control group,P<0.05.4)The inci-dence rates of premature birth(9/55,16.36%)and miscarriage(1/55,1.82%)in the observation group were lower than those in the premature birth control group(14/55,25.45%)and miscarriage(4/55,7.27%),while the full-term pregnancy rate(45/55,81.82%)was higher than that in the control group(37/55,67.27%),and the difference was not significant,P>0.05.Conclusion:The application of phloroglucinol and progesterone injection to patients with threatened miscarriage can alleviate clinical symptoms,improve uterine artery blood flow parameters,progesterone levels,and increase full-term pregnan-cy rate.It is worth applying.