首页|间苯三酚与黄体酮注射液联用对先兆流产患者妊娠结局的影响

间苯三酚与黄体酮注射液联用对先兆流产患者妊娠结局的影响

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目的:观察并分析对先兆流产患者应用间苯三酚与黄体酮注射液,对其妊娠结局的影响。方法:在利津县妇幼保健院共开展为期 2 年的研究,开始时间 2022 年 3 月,结束时间 2024 年 2 月,样本对象选定 110 例先兆流产患者,以治疗方法差异分组处理,即对照组(n=55)、观察组(n=55),分别予以黄体酮注射液、黄体酮注射液+间苯三酚。对比两组症状缓解时间、子宫动脉血流参数、孕激素水平、妊娠结局。结果:1)联合应用间苯三酚+黄体酮注射液后,观察组各项症状缓解时间均短于对照组,P<0。05。2)观察组子宫动脉血流各参数水平均低于对照组,P<0。05。3)观察组各项孕激素水平均高于对照组,P<0。05。4)观察组早产(16。36%)、流产(1。82%)发生率均低于对照组(25。45%、7。27%),足月妊娠率(81。82%)高于对照组(67。27%),差异不明显,P>0。05。结论:对先兆流产患者应用间苯三酚与黄体酮注射液,能够减轻患者临床症状,改善子宫动脉血流参数、孕激素水平,提高足月妊娠率,值得临床应用。
The effect of combined use of phloroglucinol and progesterone injection on pregnancy outcomes in patients with threatened miscarriage
Objective:To observe and analyze the effects of the use of injection of phloroglucinol and progesterone on pregnancy outcomes in patients with threatened miscarriage.Methods:A 2-year study was carried out in Lijin County Maternal and Child Health Hospital,starting from March 2022 and ending in February 2024.110 patients with threatened miscarriage were select-ed as the sample subjects,and were divided into two groups according to different treatment methods:the control group(n=55)and the observation group(n=55),receiving progesterone injection,progesterone injection and phloroglucinol,respective-ly.Compare the time of symptom relief,uterine artery blood flow parameters,progesterone levels and pregnancy outcomes be-tween two groups.Results:1)After the combined application of phloroglucinol and progesterone injection,the relief time of various symptoms in the observation group was shorter than that in the control group,P<0.05.2)The levels of various pa-rameters of uterine artery blood flow in the observation group were lower than those in the control group,P<0.05.3)The levels of various progesterones in the observation group were higher than those in the control group,P<0.05.4)The inci-dence rates of premature birth(9/55,16.36%)and miscarriage(1/55,1.82%)in the observation group were lower than those in the premature birth control group(14/55,25.45%)and miscarriage(4/55,7.27%),while the full-term pregnancy rate(45/55,81.82%)was higher than that in the control group(37/55,67.27%),and the difference was not significant,P>0.05.Conclusion:The application of phloroglucinol and progesterone injection to patients with threatened miscarriage can alleviate clinical symptoms,improve uterine artery blood flow parameters,progesterone levels,and increase full-term pregnan-cy rate.It is worth applying.

Threatened miscarriagePhlorotriolProgesterone injectionPregnancy outcome

王俊娥

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利津县妇幼保健院,山东 东营 257400

先兆流产 间苯三酚 黄体酮注射液 妊娠结局

2024

中外女性健康研究
武汉大学

中外女性健康研究

ISSN:2096-0417
年,卷(期):2024.(8)