首页|子宫动脉血流动力学指标与子宫内膜异位症的关系及对病情严重程度的评估价值研究

子宫动脉血流动力学指标与子宫内膜异位症的关系及对病情严重程度的评估价值研究

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目的:分析子宫动脉血流动力学指标与子宫内膜异位症的关系及对病情严重程度的评估价值。方法:在本院自 2020 年 6月至 2022 年 6 月收治的子宫内膜异位症患者中选择与研究相符的 120 例患者,将其作为观察组,同时在相同时间段选择进行健康体检的 120 例女性,将其作为对照组。检测两组入选者子宫动脉血流动力学指标,分析子宫动脉血流动力学指标与美国生殖医学协会子宫内膜异位症分期(r-AFS)评分的关系,使用ROC分析子宫动脉血流动力学指标评价子宫内膜异位症患者发生中重度粘连的效果。结果:对比对照组,观察组子宫动脉PI、PSV、EDV、Vmin均增大,RI减小(P<0。05);经多因素Logistic回归分析,子宫动脉PI、PSV、EDV、Vmin和RI均是子宫内膜异位症的独立危险因素(P<0。05);根据观察组患者的r-AFS评分分为微轻度组(35 例,r-AFS评分<16 分)和中重度组(85 例,r-AFS评分≥16 分);中重度组子宫动脉PI、PSV、EDV、Vmin均大于微轻度组,RI小于微轻度组(P<0。05);经Pearson相关性分析,子宫内膜异位症患者r-AFS评分与子宫动脉PSV呈正相关(P<0。05),与RI呈负相关(P<0。05);在 120 例子宫内膜异位症患者中,经手术确诊发生中重度粘连 32 例;经ROC曲线分析,子宫动脉PSV联合RI诊断子宫内膜异位症发生中重度粘连的AUC为 0。915。结论:子宫动脉血流动力学指标与子宫内膜异位症的发生、发展密切相关,其中PSV和RI有助于评估病情严重程度,两者联合诊断中重度粘连的效能较好,可为疾病的诊治提供依据。
Study on the relationship between uterine arterial blood flow dynamics and endometriosis and the value of evaluating the severity of the disease
Objective:To analyze the relationship between uterine arterial blood flow dynamics and endometriosis and its value in evaluating the severity of the disease.Methods:A total of 120 patients with endometriosis in our hospital from June 2020 to June 2022 were selected as the observation group,and 120 women who underwent physical examination at the same time were selected as the control group.The hemodynamics indexes of uterine arteries in the two groups were detected.ROC was used to analyze the hemodynamic indexes of uterine artery to evaluate the effect of moderate and severe adhesion in patients with endo-metriosis.Results:Compared with the control group,the uterine artery PI,PSV,EDV and Vmin in the observation group were increased,while RI was decreased,with statistical significance(P<0.05).Multiple Logistic regression analysis showed that PI,PSV,EDV,Vmin and RI were independent risk factors for endometriosis(P<0.05).According to the r-AFS score of the observation group,patients were divided into mild group(35 cases,r-AFS score<16 points)and moderate to severe group(85 cases,r-AFS score≥16 points).PI,PSV,EDV and Vmin of uterine artery in moderate to severe group were higher than those in mild group,and RI was lower than those in mild group,with statistical significance(P<0.05).According to Pearson correlation analysis,r-AFS score of endometriosis patients was positively correlated with uterine artery PSV(P<0.05),and negatively correlated with RI(P<0.05).Among 120 patients with endometriosis,32 patients with moderate to se-vere adhesions were confirmed by surgery.According to ROC curve analysis,the AUC of uterine artery PSV combined with RI in the diagnosis of moderate and severe adhesion in endometriosis was 0.915.Conclusion:The hemodynamic indexes of uterine arteries are closely related to the occurrence and development of endometriosis,among which PSV and RI are helpful to evalu-ate the severity of the disease,and the combined diagnosis of moderate and severe adhesion is more effective,which can provide a basis for the diagnosis and treatment of the disease.

EndometriosisUterine arteryHemodynamicsAdhesion

彭敏、蔡慧玲

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重庆市巫山县人民医院妇科,重庆 404700

子宫内膜异位症 子宫动脉 血流动力学 粘连

2024

中外女性健康研究
武汉大学

中外女性健康研究

ISSN:2096-0417
年,卷(期):2024.(8)