Effect of baogong zhixue granule on sex hormone and quality of life in perimenopausal dysfunctional uterine bleeding
Objective:To observe and analyze the effect of Baogong Zhixue Granule on sex hormone and quality of life in perim-enopausal dysfunctional uterine bleeding and its value in treatment.Methods:152 cases of perimenopausal dysfunctional uterine bleeding cases in our hospital from January 2023 to February 2024 were selected as the research object,control group of 76 ca-ses(ethinylestradiol cyproterone tablets treatment)and observation group of 76 cases(Baogong Zhixue particles combined with ethinylestradiol cyproterone tablets treatment),compared two groups before and after treatment with hemostasis time,sex hormone levels,quality of life and clinical efficacy.Results:The time of control hemostasis and complete hemostasis in the ob-servation group was shorter than that in the control group.After treatment,P(3.47±1.14)nmol/L,E2(110.22±10.06)pmol/L,FSH(83.62±7.82)U/L,LH(40.31±5.06)mIU/mL,MENQOL score(83.21±7.69)and MRS score(80.47±7.52)were lower than those of the control group,while WHOQOL-BRIEF score(104.39±12.63)and total effective rate were higher than those of the control group,the difference was statistically significant(P<0.05).Conclusion:Baogong Zhix-ue Granule in the adjuvant treatment of perimenopausal dysfunctional uterine bleeding can promote the secretion of sex hor-mones,shorten the time of abnormal uterine bleeding,improve the quality of life of patients,and improve the curative effect of perimenopausal dysfunctional uterine bleeding.