质谱成像技术在药用植物研究中的应用
Application of mass spectrometry imaging technology in medicinal plants research
袁俊鹏 1马艳 1郭庆梅1
作者信息
- 1. 山东中医药大学药学院,济南 250355
- 折叠
摘要
药用植物中含有种类繁多、数量庞大、功能各异的次生代谢产物,在疾病治疗中发挥了重要作用.传统分析方法只能对药用植物中次生代谢物进行定性和定量研究,对其空间分布研究缺乏直接手段,质谱成像技术的出现为此提供了可能.本文综述了目前应用于药用植物研究的主要质谱成像技术及其在药用植物次生代谢物、药用植物胁迫防御研究等方面的研究成果,并对其在药用植物研究中的应用前景进行了展望.
Abstract
Plants contain a wide range of metabolites with large quantities and different secondary metab-olites,which play an important role in disease treatment.As a drug research resource,more and more at-tention has been paid.Traditional analytical methods can only conduct qualitative and quantitative re-search on metabolites,and there is no direct means to study their spatial distribution.The emergence of mass spectrometry imaging technology provides a possibility for this.In this paper,the main mass spec-trometry imaging techniques used in the research of medicinal plants and their research achievements in the research of medicinal plant metabolites and medicinal plant stress defense are reviewed,and their ap-plication prospects in the research of medicinal plants are prospected.
关键词
质谱成像技术/药用植物/基质辅助激光解析电离质谱/二次离子质谱/解吸电喷雾电离质谱Key words
mass spectrometry imaging/medicinal plants/MALDI-MSI/SIMS/DESI-MSI引用本文复制引用
基金项目
山东省自然科学基金(ZR2021MH123)
出版年
2024
NETL
NSTL
万方数据