Abstract
The basis of modem pharmacology is the human ability to exploit the production of specialized metabolites from medical plants,for example,terpenoids,alkaloids,and phenolic acids.How-ever,in most cases,the availability of these valuable compounds is limited by cellular or or-ganelle barriers or spatio-temporal accumulation patterns within different plant tissues.Transcription factors(TFs)regulate biosynthesis of these speci-alized metabolites by tightly controlling the ex-pression of biosynthetic genes.Cutting-edge technologies and/or combining multiple strategies and approaches have been applied to elucidate the role of TFs.In this review,we focus on recent progress in the transcription regulation mechanism of representative high-value products and describe the transcriptional regulatory network,and future perspectives are discussed,which will help de-velop high-yield plant resources.
基金项目
国家重点研发计划(2023YFC3503900)
国家自然科学基金(82073963)
国家自然科学基金(82204554)
浙江省自然科学基金(LQ23H280010)
National Ten Thousands Program for Leading Talents of Science and Technology Innovation()
National Young Qihuang Scholars Training Program()
Zhejiang Provincial Program for the Cultivation of High Level Innovative Health Talents()
Science Research Fund of Administration of Traditional Chinese Medicine of Zhejiang Province(2023ZR089)