植物学报(英文版)2024,Vol.66Issue(3) :510-531.DOI:10.1111/jipb.13634

Molecular regulation of the key specialized metabolism pathways in medicinal plants

Min Shi Siwei Zhang Zizhen Zheng Itay Maoz Lei Zhang Guoyin Kai
植物学报(英文版)2024,Vol.66Issue(3) :510-531.DOI:10.1111/jipb.13634

Molecular regulation of the key specialized metabolism pathways in medicinal plants

Min Shi 1Siwei Zhang 1Zizhen Zheng 1Itay Maoz 2Lei Zhang 3Guoyin Kai1
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作者信息

  • 1. Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health,Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation,School of Pharmaceutical Sciences,Jinhua Academy,Zhejiang Chinese Medical University,Hangzhou 310053,China
  • 2. Department of Postharvest Science,Agricultural Research Organization,Volcani Center,Rishon,LeZion 7505101,Israel
  • 3. Department of Pharmaceutical Botany,School of Pharmacy,Naval Medical University,Shanghai 200433,China
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Abstract

The basis of modem pharmacology is the human ability to exploit the production of specialized metabolites from medical plants,for example,terpenoids,alkaloids,and phenolic acids.How-ever,in most cases,the availability of these valuable compounds is limited by cellular or or-ganelle barriers or spatio-temporal accumulation patterns within different plant tissues.Transcription factors(TFs)regulate biosynthesis of these speci-alized metabolites by tightly controlling the ex-pression of biosynthetic genes.Cutting-edge technologies and/or combining multiple strategies and approaches have been applied to elucidate the role of TFs.In this review,we focus on recent progress in the transcription regulation mechanism of representative high-value products and describe the transcriptional regulatory network,and future perspectives are discussed,which will help de-velop high-yield plant resources.

Key words

biosynthesis/medicinal plants/omics/secondary metabolism/transcription factors

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基金项目

国家重点研发计划(2023YFC3503900)

国家自然科学基金(82073963)

国家自然科学基金(82204554)

浙江省自然科学基金(LQ23H280010)

National Ten Thousands Program for Leading Talents of Science and Technology Innovation()

National Young Qihuang Scholars Training Program()

Zhejiang Provincial Program for the Cultivation of High Level Innovative Health Talents()

Science Research Fund of Administration of Traditional Chinese Medicine of Zhejiang Province(2023ZR089)

出版年

2024
植物学报(英文版)
中国植物学会

植物学报(英文版)

CSTPCD
影响因子:0.921
ISSN:1672-9072
参考文献量170
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