首页|Molecular regulation of the key specialized metabolism pathways in medicinal plants
Molecular regulation of the key specialized metabolism pathways in medicinal plants
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The basis of modem pharmacology is the human ability to exploit the production of specialized metabolites from medical plants,for example,terpenoids,alkaloids,and phenolic acids.How-ever,in most cases,the availability of these valuable compounds is limited by cellular or or-ganelle barriers or spatio-temporal accumulation patterns within different plant tissues.Transcription factors(TFs)regulate biosynthesis of these speci-alized metabolites by tightly controlling the ex-pression of biosynthetic genes.Cutting-edge technologies and/or combining multiple strategies and approaches have been applied to elucidate the role of TFs.In this review,we focus on recent progress in the transcription regulation mechanism of representative high-value products and describe the transcriptional regulatory network,and future perspectives are discussed,which will help de-velop high-yield plant resources.
Min Shi、Siwei Zhang、Zizhen Zheng、Itay Maoz、Lei Zhang、Guoyin Kai
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Zhejiang Provincial International S&T Cooperation Base for Active Ingredients of Medicinal and Edible Plants and Health,Zhejiang Provincial Key TCM Laboratory for Chinese Resource Innovation and Transformation,School of Pharmaceutical Sciences,Jinhua Academy,Zhejiang Chinese Medical University,Hangzhou 310053,China
Department of Postharvest Science,Agricultural Research Organization,Volcani Center,Rishon,LeZion 7505101,Israel
Department of Pharmaceutical Botany,School of Pharmacy,Naval Medical University,Shanghai 200433,China
国家重点研发计划国家自然科学基金国家自然科学基金浙江省自然科学基金National Ten Thousands Program for Leading Talents of Science and Technology InnovationNational Young Qihuang Scholars Training ProgramZhejiang Provincial Program for the Cultivation of High Level Innovative Health TalentsScience Research Fund of Administration of Traditional Chinese Medicine of Zhejiang Province
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