Structural insights into the Oryza sativa cation transporters HKTs in salt tolerance

扫码查看

原文链接

万方数据
维普

外文摘要：The high-affinity potassium transporters(HKTs),selectively permeable to either Na+alone or Na+/K+,play pivotal roles in maintaining plant Na+/K+homeostasis.Although their involvement in salt tolerance is widely reported,the molec-ular underpinnings of Oryza sativa HKTs remain elusive.In this study,we elucidate the structures of OsHKT1;1 and OsHKT2;1,representing two distinct classes of rice HKTs.The dimeric as-sembled OsHKTs can be structurally divided into four domains.At the dimer interface,a half-helix or a loop in the third domain is coordinated by the C-terminal region of the opposite subunit.Additionally,we present the structures of OsHKT1;5 salt-tolerant and salt-sensitive var-iants,a key quantitative trait locus associated with salt tolerance.The salt-tolerant variant of OsHKT1;5 exhibits enhanced Na+transport capability and displays a more flexible con-formation.These findings shed light on the mo-lecular basis of rice HKTs and provide insights into their role in salt tolerance.

外文关键词：

HKTsalt-tolerantstructure

作者：

Ran Gao、Yutian Jia、Xia Xu、Peng Fu、Jiaqi Zhou、Guanghui Yang

展开 >

作者单位：

State Key Laboratory of Plant Environmental Resilience,Frontiers Science Center for Molecular Design Breeding,College of Biological Sciences,China Agricultural University,Beijing 100193,China

基金：

国家重点研发计划国家自然科学基金Chinese Universities Scientific Fund fundsChinese Universities Scientific Fund fundsYoung Elite Scientists Sponsorship Program by China Association for Science and TechnologyChina Agriculture University Young Talent Program in Life SciencePinduoduo-China Agricultural University Research Fund

项目编号：

2022YFA1303400321711882023RC0122023TC190008PC2023B01010

出版年：

2024

DOI：

10.1111/jipb.13632

植物学报(英文版)

中国植物学会

植物学报(英文版)

CSTPCD

影响因子：0.921

ISSN：1672-9072

年,卷(期)：2024.66(4)

参考文献量36