Abstract
It is generally accepted that jasmonate-ZIM do-main(JAZ)repressors act to mediate jasmonate(JA)signaling via CORONATINE-INSENSITIVE1(COI1)-mediated degradation.Here,we report a cryptic signaling cascade where a JAZ repressor,FvJAZ12,mediates multiple signaling inputs via phosphorylation-modulated subcellular trans-location rather than the COI1-mediated degradation mechanism in strawberry(Fragaria vesca).FvJAZ12 acts to regulate flavor metabolism and defense response,and was found to be the target of FvMPK6,a mitogen-activated protein kinase that is capable of responding to multiple signal stimuli.FvMPK6 phosphorylates FvJAZ12 at the amino acid residues S179 and T183 adjacent to the PY residues,thereby attenuating its nuclear accumulation and relieving its repression for FvMYC2,which acts to control the expression of lipoxygenase 3(FvLOX3),an important gene in-volved in JA biosynthesis and a diverse array of cellular metabolisms.Our data reveal a previously unreported mechanism for JA signaling and deci-pher a signaling cascade that links multiple signaling inputs with fruit trait development.
基金项目
National Key Research and Development Program(2022YFD2100102)
Tianchi Talent Program(2023)()
Beijing Natural Science Foundation(6232019)
National Key Research and Development Program(2019YFD1000200)
Construction of Beijing Science and Technology Innovation and Service Capacity in Top Subjects(CEFFPXM2019_014207_000032)
NETL
NSTL
万方数据