首页|A vicinal oxygen chelate protein facilitates viral infection by triggering the unfolded protein response in Nicotiana benthamiana

A vicinal oxygen chelate protein facilitates viral infection by triggering the unfolded protein response in Nicotiana benthamiana

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Vicinal oxygen chelate(VOC)proteins are members of an enzyme superfamily with dioxygenase or non-dioxygenase activities.However,the biological functions of VOC proteins in plants are poorly un-derstood.Here,we show that a VOC in Nicotiana benthamiana(NbVOC1)facilitates viral infection.NbVOC1 was significantly induced by infection by beet necrotic yellow vein virus(BNYW).Transient overexpression of NbVOC1 or its homolog from Beta vulgaris(BvVOC11)enhanced BNYW infection in N.benthamiana,which required the nuclear localization of VOC1.Consistent with this result,overexpressing NbVOC1 facilitated BNYW in-fection,whereas,knockdown and knockout of NbVOC1 inhibited BNYW infection in transgenic N.benthamiana plants.NbVOC1 interacts with the basic leucine zipper transcription factors bZIP17/28,which enhances their self-interaction and DNA binding to the promoters of unfolded protein re-sponse(UPR)-related genes.We propose that bZIP17/28 directly binds to the NbVOC1 promoter and induces its transcription,forming a positive feedback loop to induce the UPR and facilitating BNYW infection.Collectively,our results demon-strate that NbVOC1 positively regulates the UPR that enhances viral infection in plants.

beet necrotic yellow vein virusbZIP1 7/28Nicotiana benthamianaunfolded protein responseVOC1

Zhihong Guo、Ning Jiangt、Menglin Li、Hongfang Guo、Qi Liu、Xinyu Qin、Zongying Zhang、Chenggui Han、Ying Wang

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Ministry of Agriculture and Rural Affairs Key Laboratory of Pest Monitoring and Green Management,College of Plant Protection,China Agricultural University,Beijing 100193,China

National Natural Science Foundation of ChinaNational Natural Science Foundation of ChinaChina Agricultural Industry Technology System

3227016531872921CARS-170304

2024

10.1111/jipb.13667

植物学报(英文版)
中国植物学会

植物学报(英文版)

CSTPCD
影响因子：0.921
ISSN：1672-9072
年,卷(期)：2024.66(7)
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