Abstract
Rice stripe mosaic virus(RSMV)is an emerging pathogen which significantly reduces rice yields in the southern region of China.It is transmitted by the leafhopper Recilia dorsalis,which overwinters in rice fields.Our field investigations revealed that RSMV infection causes delayed rice heading,re-sulting in a large number of green diseased plants remaining in winter rice fields.This creates a favorable environment for leafhoppers and viruses to overwinter,potentially contributing to the rapid spread and epidemic of the disease.Next,we ex-plored the mechanism by which RSMV manipulates the developmental processes of the rice plant.A rice heading-related E3 ubiquitin ligase,Heading date Associated Factor 1(HAF1),was found to be hijacked by the RSMV-encoded P6.The impair-ment of HAF1 function affects the ubiquitination and degradation of downstream proteins,HEADING DATE 1 and EARLY FLOWERING3,leading to a delay in rice heading.Our results provide new insights into the development regulation-based molecular interactions between virus and plant,and highlights the importance of understanding virus-vector-plant tripartite interactions for effective disease management strategies.
基金项目
National Natural Science Foundation of China(32222071)
National Natural Science Foundation of China(32072388)
National Key Research and Development Program of China(2022YFA1304400)
Natural Science Foundation of Guangdong Province(2021A1515110363)
Natural Science Foundation of Guangdong Province(2022A1515010770)
Natural Science Foundation of Guangdong Province(2023A1515012030)
Guangzhou Science and Technology Program(2023B03J1313)
万方数据