Research Progress on Genes Related to Flavonoids Biosynthesis in Herba Epi medii
Herba Epimedii is a traditional Chinese herb medicine(TCM)with a long history.Research on Herba Epimedii has attracted much attention in China due to its high medicinal value.C8-prenylated flavonol glycosides(PFGs)have been demonstrated to be the main bioactive components in Epimedium brevicomu,and their content determines the medicinal quality.Understanding the biosynthesis pathway of PFGs,exploring genes related to PFGs content,and elu-cidating the regulatory mechanisms of PFGs biosynthesis pathway is fundamental and essential for improving the quality of E.brevicomu.Here,we provide a comprehensive review of the research on structural and transcriptional factor genes related to the biosynthesis of PFGs,which not only contributes to unravel the regulatory mechanisms related to PFGs content,but also lay a foundation for research on molecular breeding and the synthetic biology in Epimedium plants.