Maize(Zea mays)is the main crop in China,and drought is a primary abiotic stress during its growth,resulting in direct reduction in grain yield and quality,thereby posing a threat to food security within the global climate context.At present,global climate change leads to extreme weather events,which aggravates the adverse effects on yield.There-fore,it is imperative to identify drought-resistant germplasm resources,elucidate the molecular mechanisms of drought stress response,and breed drought-resistant varieties.Here,we review recent advances in the genetic dissection of drought resistance in maize using methods such as genome-wide association study,quantitative trait locus gene cloning and multi-omics analysis.Additionally,we introduce potential strategies for genetic improvement of drought resistance by leveraging the identified genetic resources while discussing future perspectives within this research area.