In the era of artificial intelligence,the education paradigm is undergoing unprecedented changes.The generative AI technology,represented by ChatGPT,Wenxin,Flytek Spark and Sora,is developing rapidly.It simulates the way of human thinking and creativity,and can automatically generate text,images,audio,video and other content.As as the main position of technical personnel training,vocational colleges face major challenges in curriculum reform.Based on the background analysis of the era of artificial intelligence,the challenges of curriculum reform in the formulation and innovation of curriculum standards,the updating and reconstruction of teaching materials,the use of digital resources and ethics,taking the application of Informatization in Kindergarten in preschool education in higher vocational colleges as an example.It puts forward to carry out special training of teachers'digital literacy,integrate new technologies and update the content of teaching materials,and actively explore the practical path of man-machine cooperative teaching mode,so as to improve the talent training mode in higher vocational colleges.